Evaluation of the efficacy of CIMR (BonAir) verses Ecoquest's low ozone System in Reducing Murine Norovirus Titers Performed by Dr. Lela Riley, RADIL LLC, Columbia MO November 18, 2008
Introduction
Members of the genus Norovirus are nonenveloped viruses with a linear, positive‐sense, single‐stranded RNA genome. Noroviruses are in the family Caliciviridae, which also includes the genera Sapovirus, Lagovirus, and Vesivirus. Formerly known as "Norwalk‐like viruses" or "small round structured viruses," noroviruses cause acute gastroenteritis in humans, typically lasting 24 to 48 h, and infect people of all ages.
Recently, the first murine norovirus, was isolated from mice. This newly described pathogen of mice can be grown in cell culture, providing the first example of a norovirus that can be cultured in vitro. In these studies, the efficacy of CIMR® verses Ecoquest’s low ozone platform has been evaluated against Murine norovirus (MNV), as a representative of the Caliciviridae family, using an in vitro culture system.